Anti-SLC39A6抗體,雌激素調(diào)節(jié)蛋白LIV1/鋅轉(zhuǎn)運(yùn)蛋白抗體產(chǎn)品介紹：LIV-1 is expressed as two isoforms. LIV-1 is a multi-pass cell membrane protein that is 749 amino acids in length and is expressed abundantly in breast, prostate, placenta, kidney, pituitary and corpus callosum, as well as in cells derived from various types of cancers affecting the glands, cervix and lungs. LIV-1 is a member of the ZIP transporter protein family which consists of 14 members that transport zinc. LIV-1 transports zinc from its position on the plasma membrane into the cytosol of the cell and contains a histidine-rich transmembrane domain which is thought to bind zinc and aid in its transportation. LIV-1 is thought to be important for zinc uptake in neuroblastoma cells and may also be crucial for maintaining zinc homeostasis, a process which aids in the prevention of cancer and disease. Activated estrogen receptors are thought to regulate LIV-1 expression at the level of transcription, via the mRNA precursor to LIV-1 which associates with estrogen receptors that are activated by growth factors and estradiol. LIV-1 is upregulated in hormone-rich tissue, including breast and cervical cancer, where it is thought to affect cell motility and may play an important role in tumor development and metastasis. Conversely, less aggressive tumors may contain high levels of LIV-1 that could lead to apoptosis, indicating a dual role for LIV-1 in tumor suppression. 

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保存條件：Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
連續(xù)使用時4°C存儲，保質(zhì)期六個月，*存儲時建議分裝為10ul以上小包裝-20°C存儲，并避免反復(fù)凍融，保質(zhì)期一年。

產(chǎn)品名稱 Anti-SLC39A6抗體,雌激素調(diào)節(jié)蛋白LIV1/鋅轉(zhuǎn)運(yùn)蛋白抗體

產(chǎn)品編號 BYK-1895R

英文名稱 SLC39A6
中文名稱 雌激素調(diào)節(jié)蛋白LIV1/鋅轉(zhuǎn)運(yùn)蛋白抗體
別    名 LIV1; LIV 1; LIV-1; solute carrier family 39, member 6; solute carrier family 39 (zinc transporter), member 6 isoform 1; Zinc transporter ZIP6; Zrt- and Irt-like protein 6; ZIP-6; Endoplasmic reticulum membrane-linked protein; Ermelin; S39A6_HUMAN.
研究領(lǐng)域 信號轉(zhuǎn)導(dǎo)           

抗體來源 Rabbit or Mouse
克隆類型 Polyclonal or Monoclonal
交叉反應(yīng)、產(chǎn)品應(yīng)用 （具體交叉反應(yīng)與產(chǎn)品應(yīng)用請）

    Anti-SLC39A6抗體,雌激素調(diào)節(jié)蛋白LIV1/鋅轉(zhuǎn)運(yùn)蛋白抗體更多優(yōu)質(zhì)產(chǎn)品有：

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細(xì)胞因子信號傳導(dǎo)抑制蛋白3抗體 Anti-SOCS3
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