Anti-SIAH3抗體,SIAH3蛋白抗體說明資料產品介紹：Members of the SINA (seven in absentia) protein family are components of ubiquitin ligase complexes, which target proteins for proteasomal degradation. SIAH3 (seven in absentia homolog 3) is a 269 amino acid protein that belongs to the SINA family, contains one SIAH-type zinc finger and is encoded by a gene located on human chromosome 13. Comprising nearly 4% of human DNA, chromosome 13 contains around 114 million base pairs and 400 genes. Key tumor suppressor genes on chromosome 13 include the breast cancer susceptibility gene, BRCA2, and the RB1 (retinoblastoma) gene. RB1 encodes a crucial tumor suppressor protein which, when defective, leads to malignant growth in the retina and has been implicated in a variety of other cancers. The gene SLITRK1, which is associated with Tourette syndrome, is on chromosome 13. As with most chromosomes, polysomy of part or all of chromosome 13 is deleterious to development and decreases the odds of survival. Trisomy 13, also known as Patau syndrome, is quite deadly and the few who survive past one year suffer from permanent neurologic defects, difficulty eating and vulnerability to serious respiratory infections. 

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保存條件：Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
連續使用時4°C存儲，保質期六個月，*存儲時建議分裝為10ul以上小包裝-20°C存儲，并避免反復凍融，保質期一年。

產品名稱 Anti-SIAH3抗體,SIAH3蛋白抗體說明資料

產品編號 BYK-17481R

英文名稱 SIAH3
中文名稱 SIAH3蛋白抗體
別    名 FLJ39203; Gm912; RP11-480G1.1; Seven in absentia homolog 3; Siah-3; SIAH3; SIAH3_HUMAN.
研究領域 腫瘤  細胞生物  免疫學  神經生物學               

抗體來源 Rabbit or Mouse
克隆類型 Polyclonal or Monoclonal
交叉反應、產品應用 （具體交叉反應與產品應用請）

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