博研生物抗體，“G蛋白偶聯受體109A抗體,Anti-GPR109A/HM74A抗體”應用于IHC、WB、 IF、IP、ELISA，質量保證，無效免費退換，另外本公司生產經營各種標記二抗、免疫印跡常用試劑、免疫組化常用試劑，咨詢！

產品介紹：

【產品名稱】：G蛋白偶聯受體109A抗體,Anti-GPR109A/HM74A抗體

【產品類型】：一抗

【產品編號】：BYk-2582R                    

【相關標記】: HRP Biotin Gold RBITC AP FITC Cy3 Cy5 Cy5.5 Cy7 PE PE-Cy3 PE-CY5 PE-CY5.5 PE-CY7 APC Alexa Fluor 350 Alexa Fluor 488 Alexa Fluor 555 Alexa Fluor 647

【性 狀】： Lyophilized or Liquid

【濃 度】： 1mg/1ml

【亞 型】： IgG

【規 格】：0.1ml/100ug，0.2ml/200ug

【抗體來源】： Rabbit OR MOUSE

【克隆類型】： polyclonal or monoclonal

【產品用途】：科研實驗，用于免疫組化實驗，WB實驗、IF、IP、ELISA實驗，相應的標記抗體有HRP標記抗體，FITC標記，BIO等。

【貯 存】： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

【信息詳情】： Acts as a high affinity receptor for both nicotinic acid （also known as niacin） and （D）-beta-hydroxybutyrate and mediates increased adiponectin secretion and decreased lipolysis through G（i）-protein-mediated inhibition of adenylyl cyclase. This pharmacological effect requires nicotinic acid doses that are much higher than those provided by a normal diet. Mediates nicotinic acid-induced apoptosis in mature neutrophils. Receptor activation by nicotinic acid results in reduced cAMP levels which may affect activity of cAMP-dependent protein kinase A and phosphorylation of target proteins, leading to neutrophil apoptosis.

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