背景介紹：GRO beta is a member of the CXC, or chemokine class. It contains the ELR domain immediay preceding the first cysteine residue near the amino terminus. Other chemokines in this group include IL8, GRO alpha/beta/gamma, mouse KC, ENA78, GCP2, PBP/CTAPIII/beta TG/NAP2. These chemokines act primarily on neutrophils as chemoattractants and activators, including neutrophil degradation with release of myloperoxidase and other enzymes. GRO beta was originally identified as a heparin-binding protein secreted from a murine macrophage cell line in response to endotoxin stimulation. GRO beta is an approximay 8 kDa polypeptide of 73 amino acids. The precursor form of GRO beta consists of 100 amino acids. To generate the mature GRO beta, the precursor cleaves its amino terminal 27 amino acids. GRO beta shows 60% amino acid homology to human GRO alpha and GRO gamma.

別名：C-X-C motif chemokine 2; Chemokine (C X C motif) ligand 2; Chemokine, CXC motif, ligand 2; CINC 2a; CINC2a; CINC3; CXC chemokine; CXCL 2; CXCL2; MIP2; MIP 2; MIP-2; Cytokine-induced neutrophil chemoattractant 3; GRO 2; GRO b; GRO protein, beta; Gro-beta; GRO2; GRO2 oncogene; GROb; GRObeta; GRO Beta; Growth regulated protein beta; GROX; Macrophage inflammatory protein 2 alpha; Macrophage inflammatory protein 2; Melanoma growth stimulatory activity beta; MGSA b; MGSA beta; MGSAbeta; MIP 2; MIP 2a; MIP2 alpha; MIP2; MIP2A; MIP2alpha; SCYB 2; Scyb; SCYB2; Small inducible cytokine subfamily B, member 2.     

巨噬細胞炎癥蛋白2抗體，Anti-CXCL2抗體簡單介紹：

產(chǎn)品編號：BYK-20208R

英文名稱：Anti-CXCL2
中文名稱：巨噬細胞炎癥蛋白2抗體

產(chǎn)品規(guī)格：50ul；100ul；200ul；1ml，*

抗體來源 Rabbit or Mouse

克隆類型 Polyclonal or Monoclonal

交叉反應、產(chǎn)品應用 （具體交叉反應與產(chǎn)品應用請或添加客服直接索取）

性    狀 Lyophilized or Liquid
濃    度 1mg/ml

巨噬細胞炎癥蛋白2抗體，Anti-CXCL2抗體產(chǎn)品信息：

博研生物小課堂：

常用激光器對應熒光素的選擇：

藍色激光器熒光素（488nm）：Alexa Fluor 488、FITC、PerCP、PerCP-Cy5.5、PE、PE-Cy5.5、PE-Cy5、PE-Cy7

紅色激光器熒光素（633nm）：APC、Cy5、APC-Cy5.5、APC-Cy7、Alexa Fluor 647

黃色激光器熒光素（561nm）：PE、PE-Cy5.5、PE-Cy5、PE-Cy7、Cy3、Alexa Fluor 555、Alexa Fluor 594

1.陽性細胞染色分布有三種類型：細胞漿、細胞核、細胞膜表面。大部分抗原見于細胞漿，可見于整個胞漿或部分胞漿

2.陽性細胞分布可分為灶型和彌漫性

3.由于細胞內(nèi)含抗原量不同，所以染色強度不一。如果細胞之間染色強度相同，常提示其反應為非特異性

4.陽性細胞染色定位于單個細胞，且與陰性細胞相互交雜分布；而非特異性染色常不限于單個細胞，而是累及一片細胞。

5.切片邊緣、刀痕或褶皺區(qū)域，壞死或擠壓的細胞區(qū)，膠原結締組織等，常表現(xiàn)為相同的陽性染色強度，不能用于判斷陽性。

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